Student name:
Danit Levy
Advisor name: Dr.
Zehava Blachman
4. Results
2013 2
Medical Engineering
The Response of Peripheral Microcirculation to
Slow Breathing Guiding Device
3.3. Signals Processing
Figure 2:
Signals during a RESPeRATE session .
The signals were sampled at 500 Hz.
LDF signal was filter with Butterworth
low pass filter.
Pearson product moment Correlation (corr)
was made between respiratory and LDF
signals at different breathing rates.
Software algorithm was programmed to
display RR interval from the ECG signals.
Statistical analysis was performed using
paired t test significance level p<0.05
Figure 3
: Correlation between respiration and LDF signals at different bpm
5. Conclusions
The breathing exercise applied seems to entrain the cardiovascular system mostly
at breathing rate of 6 8 bpm. At lower rates, vasomotion frequencies, the known
spontaneous oscillation of the arterioles, dominates the capillary flow.
Breathing rate is associated with tissue oxygenation. At low enough breathing
rate(<6 bpm) the peripheral microcirculation fails to provide blood supply to the
peripheral tissues.
The results may have a clinical potential in expressing the cardio pulmonary control
of blood supply to the peripheral microcirculation.
Figure 4
: tcPO
Vs bpm for
subjects who reach 5 bpm.
Advance of time
268...,222,223,224,225,226,227,228,229,230,231 211,212,213,214,215,216,217,218,219,220,...1